Corsidus can provide you with a comprehensive array of in vitro assays through an integrated network of strategic partners. These tests will generate necessary information on preliminary pharmacology, toxicology, solubility and stability and identify molecules that exhibit preferred ADME properties. Corsidus will guide you through the process of selecting the most appropriate set of in vitro assays to assess your drug candidate and will provide you with fully interpreted reports, expert opinion and recommendations for follow on studies.
Some of the In Vitro ADME assays that we provide are:
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Caco-2 cell monolayer absorption assay
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PAMPA absorption assay
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Enzyme and receptor selectivity panel assays
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Assessment of stability in animal or human blood plasma
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CYP450 interaction studies (inhibition and induction studies)
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Metabolic profiling using human and animal hepatocytes and microsomes
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Measurement of aqueous solubility and stability
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Plasma protein binding characteristics of the drug candidate
To obtain additional information on our In Vitro assay capabilities please call Corsidus at 1-888-367-5212.
